Third International Conference on Spoken Language Processing (ICSLP 94)

Yokohama, Japan
September 18-22, 1994

Speech Production: Insights from a Study of Progressive Aphasia

Karalyn Patterson (1), Karen Croot (1), John R. Hodges (2)

(1) Medical Research Council, Applied Psychology Unit, Cambridge, UK
(2) Univ. of Cambridge Clinical School, Dept of Neurology, Addenbrooke's Hospital, Cambridge, UK

Neurodegenerative disease can result in a primary language disturbance, typically called primary progressive aphasia, of which two distinctly different patterns have been described. Non-fluent and fluent progressive aphasia [1,2] bear some similarities to non-fluent and fluent aphasia resulting from cerebro-vascular accident (CVA), but often reveal especially clear-cut, circumscribed language deficits. In this paper, we focus on the object naming performance of two patients, one with each form of progressive aphasia. Both patients' naming showed a marked decline over a two/three-year period. The anomia of the fluent case can be explained entirely by progressive loss of features of knowledge representation for objects and words. The deficit of the nonfluent case reflects progressive difficulty in access to and retrieval from phonological representations for speech production.

Full Paper

Bibliographic reference.  Patterson, Karalyn / Croot, Karen / Hodges, John R. (1994): "Speech production: Insights from a study of progressive aphasia", In ICSLP-1994, 755-758.