ISCA Archive ICSLP 2000
ISCA Archive ICSLP 2000

Brain regions responsible for word retrieval, speech production and deficient word fluency in elderly people: a PET activation study

Itaru F. Tatsumi, Michio Senda, Kenji Ishii, Masahiro Mishina, Masashi Oyama, Hinako Toyama, Keiichi Oda, Masayuki Tanaka, Yasuyuki Gondo

A PET (positron emission tomography) activation study using word-fluency tasks was administered to identify the network for word retrieval and speech production, and to explore mechanisms for word finding difficulty observed in elderly people. It was found that the left anterior insula, as opposed to Broca’s area, left premotor area, the anterior cingulate gyrus, thalamus, basal ganglia, midbrain and cerebellum constitute the network for speech production. In semantic processing for word retrieval of proper names, the left anterior temporal lobe and frontal pole (BA 10) were activated. As for the animate and inanimate name retrieval, and the syllable fluency the same areas, viz., the left inferoposterior temporal lobe (BA 37) and left inferior frontal lobe (Broca’s area), were activated.

In elderly people an activated area was generally small, and those regions activated in young people were sometimes inactive. However, an great, stable and diffuse activation was also observed. The latter may reflect an effort to compensate for deficient word retrieval. These are possible sources of word finding difficulty in the elderly.


Cite as: Tatsumi, I.F., Senda, M., Ishii, K., Mishina, M., Oyama, M., Toyama, H., Oda, K., Tanaka, M., Gondo, Y. (2000) Brain regions responsible for word retrieval, speech production and deficient word fluency in elderly people: a PET activation study. Proc. 6th International Conference on Spoken Language Processing (ICSLP 2000), vol. 2, 5-10

@inproceedings{tatsumi00_icslp,
  author={Itaru F. Tatsumi and Michio Senda and Kenji Ishii and Masahiro Mishina and Masashi Oyama and Hinako Toyama and Keiichi Oda and Masayuki Tanaka and Yasuyuki Gondo},
  title={{Brain regions responsible for word retrieval, speech production and deficient word fluency in elderly people: a PET activation study}},
  year=2000,
  booktitle={Proc. 6th International Conference on Spoken Language Processing (ICSLP 2000)},
  pages={vol. 2, 5-10}
}