Fifth International Workshop on Models and Analysis of Vocal Emissions for Biomedical Applications (MAVEBA 2007)

Florence, Italy
December 13-15, 2007

Advanced Voice Assessment. A Prospective Case-Control Study of Jitter%, Shimmer% and Qx%, Glottis Closure Cohesion Factor (Spead by Laryngograph Ltd.) and Long Time Average Spectra

Mette Pedersen (1), Kasper Munck (2)

(1) The Medical Center, Ear, Nose, Throat and Voice Unit. Copenhagen, Denmark
(2) SAS Statistical Institute, Denmark

It was suggested at the European Oto-Rhino-Laryngology conference 2007 in Vienna that voice analysis is empiric and that clinical voice treatment is not evidence based!! In the Cochrane Handbook advice for evaluation of quality of research was made: Groups are made of the quality in 3 levels: Level A (randomized controlled trial/meta-analysis): High-quality randomized controlled trial (RCT) that considers all important outcomes. High-quality meta-analysis (quantitative systematic review) using comprehensive search strategies. Level B (other evidence): A well-designed, non randomized clinical trial. A non quantitative systematic review with appropriate search strategies and well-substantiated conclusions, includes lower quality RCT's, clinical cohort studies and case-controlled studies with non biased selection of study participants and consistent findings. Other evidence, such as high-quality, historical, uncontrolled studies, or welldesigned epidemiological studies with compelling findings, is also included. Level C (consensus / expert opinion): Consensus viewpoint or expert opinion.
  The purpose of this categorization is that good studies can be structured in meta-analysis to affirm the results as it is done in e.g. cancer and cardiology research.

Full Paper (reprinted with permission from Firenze University Press)

Bibliographic reference.  Pedersen, Mette / Munck, Kasper (2007): "Advanced voice assessment. a prospective case-control study of jitter%, shimmer% and Qx%, glottis closure cohesion factor (spead by laryngograph ltd.) and long time average spectra", In MAVEBA-2007, 61-64.